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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK10
All Species:
30
Human Site:
S293
Identified Species:
55
UniProt:
Q15131
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15131
NP_001092003.2
360
41038
S293
K
H
K
F
P
W
L
S
E
A
G
L
R
L
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546775
360
41038
S293
K
H
K
F
P
W
L
S
E
A
G
L
R
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMM4
360
40942
S293
K
H
K
F
P
W
L
S
E
A
G
L
R
L
L
Rat
Rattus norvegicus
Q4KM47
358
40615
S291
K
H
K
F
P
W
L
S
E
A
G
L
R
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001103409
370
41951
S301
K
H
K
F
P
W
L
S
E
A
G
L
R
L
L
Frog
Xenopus laevis
P23437
297
33852
T231
E
V
S
W
P
G
V
T
T
M
P
D
Y
K
S
Zebra Danio
Brachydanio rerio
NP_001017622
275
30997
E209
T
L
W
Y
R
A
P
E
L
L
L
G
T
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPC0
952
108820
S821
K
H
F
Q
E
K
T
S
E
M
G
L
S
L
L
Honey Bee
Apis mellifera
XP_392973
410
46389
S319
K
Q
R
F
P
W
L
S
A
A
G
L
R
L
L
Nematode Worm
Caenorhab. elegans
Q09437
719
83549
N617
F
L
A
G
R
L
L
N
D
T
G
F
K
L
L
Sea Urchin
Strong. purpuratus
XP_783449
397
44907
S313
K
A
K
F
T
W
L
S
Q
S
G
L
R
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFT8
505
56711
D295
R
E
F
F
R
H
F
D
R
H
A
L
E
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q871M9
545
61347
P298
R
R
F
E
K
H
G
P
V
V
I
S
L
L
K
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93
N.A.
96.9
90.5
N.A.
N.A.
82.9
36.9
60.8
N.A.
21.3
63.9
25.8
63.7
Protein Similarity:
100
N.A.
N.A.
96.9
N.A.
98.8
93.6
N.A.
N.A.
89.7
53.6
69.1
N.A.
27.8
73.6
36.4
75.8
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
N.A.
100
6.6
0
N.A.
53.3
80
26.6
73.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
N.A.
100
33.3
6.6
N.A.
53.3
86.6
46.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.4
N.A.
29.7
Protein Similarity:
N.A.
N.A.
N.A.
45.5
N.A.
43.6
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
8
0
0
8
47
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
8
0
0
8
0
0
0
% D
% Glu:
8
8
0
8
8
0
0
8
47
0
0
0
8
0
0
% E
% Phe:
8
0
24
62
0
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
8
0
8
8
0
0
0
70
8
0
0
0
% G
% His:
0
47
0
0
0
16
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
62
0
47
0
8
8
0
0
0
0
0
0
8
16
8
% K
% Leu:
0
16
0
0
0
8
62
0
8
8
8
70
8
85
77
% L
% Met:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
54
0
8
8
0
0
8
0
0
0
0
% P
% Gln:
0
8
0
8
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
16
8
8
0
24
0
0
0
8
0
0
0
54
0
0
% R
% Ser:
0
0
8
0
0
0
0
62
0
8
0
8
8
0
8
% S
% Thr:
8
0
0
0
8
0
8
8
8
8
0
0
8
0
8
% T
% Val:
0
8
0
0
0
0
8
0
8
8
0
0
0
0
0
% V
% Trp:
0
0
8
8
0
54
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _